SBE 13 hydrochloride ( SBE13; SBE 13; SBE13; SBE-13 HCl )

产品货号. M17781 CAS No. 1052532-15-6

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

SBE 13 hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

SBE13 hydrochloride is an effective and specific PLK1 inhibitor (IC50: 0.2 nM); no inhibition om Aurora A kinase, Plk2/3.
产品描述

SBE-13 is a selective inhibitor of PLK1 (IC50 values are 200 pM, 875 nM and 66 μ M for PLK1, PLK3 and PLK2 respectively).
同义词

SBE13; SBE 13; SBE13; SBE-13 HCl
通路

Others
靶点

Other Targets
受体

PLK1; PLK2; PLK3
研究领域

Cancer
适应症

——

CAS Number

1052532-15-6
分子量

479.4
分子式

C24H28Cl2N2O4
纯度

98%
溶解度

DMSO : ≥ 42 mg/mL; 87.61 mM
SMILES

Clc1ncc(COc2c(OC)cc(CNCCc3cc(OC)c(OC)cc3)cc2)cc1.Cl
化学全称

N-(4-((6-chloropyridin-3-yl)methoxy)-3-methoxybenzyl)-2-(3,4-dimethoxyphenyl)ethanamine hydrochloride

1. Keppner S, et al. ChemMedChem. 2009 Nov;4(11):1806-9.2. Lange L, et al. Oncotarget. 2014 Apr 30;5(8):2263-75.

计算器

产品手册

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